6-24-2014 I have long warned against using promiscuous transposons as gene transfer vectors, especially for insects that bite people [12] (Terminator insects give wings to genome invaders, ISIS report)...Several human cell lines have been transformed, even primary human T cells using piggyBac [17]. These findings leave us little doubt that the transposon-borne transgenes in the transgenic mosquito can transfer horizontally to human cells. The piggyBac transposon was found to induce genome wide insertion mutations disrupting many gene functions.
To conclude
Transgenic mosquitoes are not the solution to eradicating dengue or malaria. On the contrary, they are among the most hazardous GMOs created, and should never be released into the wild on any commercial basis.
Researchers should consider the risks involved before embarking on a project, and science journal editors and commentators should also question whether works for publications carry risks to health and the environment. -Dr. Mae Wan Ho
http://www.isis.org.uk/Beware_the_New_Breakthrough_Transgenic_Mosquitoes.php
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Mae-Wan Ho was a geneticist known for her critical views on genetic engineering and neo-Darwinism. She has authored or co-authored a number of publications, including 10 books, such as The Rainbow and ...
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