Friday, August 21, 2020

Interview with Prof. Joseph Tritto on the virus

4-8-20 
Prof. Tritto has a respectable curriculum.  He is a doctor in urology, andrology, infertility microsurgery, and a professor in microtechnology and nanotechnology in the United Kingdom and India.  He is a visiting professor and director of nano-medicine at Amity University in New Delhi (India).
http://www.asianews.it/news-en/Prof-Tritto:-COVID-19-was-created-in-the-Wuhan-laboratory-and-is-now-in-the-hands-of-the-Chinese-military-50719.html
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7-27-20    Interview with Prof. Joseph Trittoa microsurgeon, expert in biotechnology and nanotechnology as well as president of the Wabt (World Academy of Biomedical Sciences and Technologies), a Paris academy founded under the auspices of UNESCO in 1987:
Why do you think that, from a scientific point of view, the SARS-CoV-2 virus, the cause of Covid, has no natural origins, but is a recombinant chimera created in the laboratory?
  «The hypothesis so far accredited by some scientists is that this virus was generated in nature by the combination of a bat virus and a pangolin virus.  For this to happen, however, first of all according to experts, a period of time between 40 and 200 years should pass, and then the two species involved should share the same ecological niche, which in this case it is not.  In addition there should be an intermediate host that contracts the recombined virus and transmits it to humans: but, as far as SARS-CoV-2 is concerned, it has not yet been found.  These elements would be enough to make the hypothesis of a natural origin of the virus statistically improbable and for now scientifically indemonstrable.  But there is another factor, in the SARS-CoV-2 genome, which makes this hypothesis implausible ».
And what would it be?
  "In some publications, for example in the study by researchers at the Indian Institute of Technology in New Dehli based on the genomes of patients, collected in global databases, it is shown that SARS-CoV-2 is not just a hybrid between the bat virus and that of the pangolin.  But inside there are small inserts, residues of amino acids from the HIV-1 virus, responsible for AIDS.  The presence of these inserts in a virus that developed in nature could never occur.  Not only. The SARS-CoV-2 genome presents another modification on the so-called intracellular furin site, as confirmed by two studies, one Chinese, one French-Canadian.  Both inserts have a function:  the HIV-1 insert allows SARS-CoV-2 to anchor itself to the human cell and penetrate the cell.  It is therefore presumably responsible for the high infectivity of the virus.  The modification of the furin cleavage site allows the virus to multiply inside the cell and makes it highly pathogenic ».
For what purpose was this chimera virus created? As a weapon of bioterrorism or just for scientific study purposes?
  “To give an answer you have to rewind the tape.  In 2005, after the Sars epidemic, the Wuhan Institute of Virology was born, at the head of which Prof. Shi Zheng-Li, who retrieves coronaviruses from certain bat species and recombines them with other viral components (for study) to create vaccines.  In 2010 she came into contact with American researchers led by Prof. Ralph Baric, who in turn works on recombinant viruses based on coronaviruses.  Thanks to the matrix viruses provided by Shi, Baric created in 2015 a mouse Sars-virus chimera, which has a pathogenic effect on human cells analyzed in vitro.  At that point the China-US collaboration becomes competition.  Shi wants to work on a more powerful virus to make a more powerful vaccine:  it combines a bat virus with a pangolin virus in vitro and in 2017 publishes the results of these researches in some scientific articles.  His research attracts the interest of the Chinese military and medical-biological sector that deals with biological weapons used as a deterrent for defensive and offensive purposes. Thus Shi is joined by doctors and biologists who belong to the political-military field, such as Guo Deyin, a scholar of anti-AIDS and anti-viral hepatitis vaccines and expert in genetic recombination techniques.  The introduction of the new engineered inserts into the virus genome is the result of the collaboration between the Shi team and that of Guo Deyin. The realization of this new chimera, from a scientific point of view, is a success.  So much so that, once the epidemic has broken out, the two researchers ask WHO to register it as a new virus, H-nCoV-19 (Human new Covid 19), and not as another virus derived from SARS.  It is reasonable to think that Shi acted only from the point of view of scientific prestige, without however taking into account the risks in terms of security and political-military interests that her research would have aroused ».
How would the virus escape from the laboratory instead?  For an accident, theft or intentional release into the environment?
  «I would exclude the latter, which would have damaged the Chinese, as well as theft, since the laboratories of that type are very controlled.  An accidental escape, caused by a blackout, or accidental contamination of personnel is more likely. Too many people were moving in the Wuhan laboratory: the more individuals there are, the greater the risk of contamination.  Furthermore, many of the people within it did not have specific training to treat certain viruses in a coordinated and careful way ».
Why has China never provided the complete genome of the virus to WHO or to other countries?
  “Because providing the matrix virus would have meant recognizing that SARS-CoV-2 was created in the laboratory.  In fact, the incomplete genome made available by China lacks some inserts of AIDS amino acids, which act as a smoking gun.  In the meantime however negotiations are underway between intelligence agencies of 5 countries (USA, Australia, Canada, New Zealand, Japan) and China.  Perhaps the former, in diplomatic negotiations, would be willing to postpone the Chinese responsibilities, of which they have evidence, in exchange for the possibility of obtaining the matrix virus to develop a universal vaccine ”.
Will we ever have such a vaccine?
  “It is extremely unlikely to find a single vaccine that blocks the virus, given the many mutations of SARS-CoV-2.  At the moment, 11 different strains have been identified: the A2a genetic line which developed in Europe and the B1 genetic line that took root in North America are more contagious than the 0 strain originating in Wuhan.  I therefore believe that, at most, a multivalent vaccine could be found, valid for 4-5 strains and capable of covering 70-75% of the world population ».

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5-14-20   As Dr. Antonio and others pointed out, you don’t need to use a previously used virus backbone. There’re many ways to create a virus.  For example, something’s called Directed Evolutionary Selection Process.  Basically you just engineer a number of different randomly mutated versions, put it next to the receptor binding domain of a human, let them fight it out, see which one comes out best and that one can show the high infectivity of human cells.  Was this an obscure concept?  No, actually the inventors of these processes were awarded the Nobel Prize in chemistry in 2018….
  Now we have the broad distribution of relatively low cost gene editing techniques like CRISPR CAS9. You can buy your own CRISPR do-it-yourself kit on Amazon for $169 and be cutting up bacteria, which by the way is not safe….So Australia, for example, passed regulation that a certain gene editing technique, CRISPR being one of them, can be used without any government oversight to genetically engineered plants, animals or microbes, including viruses or bacteria.  Zero regulatory oversight….
  Every time we genetically engineer there’s the possibility of a release and the release could spell catastrophe.  There are other genetically modified microorganisms that are already being released because they’re not considered to be dangerous, even though they haven’t been tested sufficiently and they may end up biting us in a way it becomes impossible to clean up or stop.

  We may want to stop the release of genetically engineered microorganisms that can mutate and change, be uncontrollable, spread around the world and be a catastrophe of some level.  I’m talking about not just viruses but also bacteria, algae, fungus and yeasts.  There’s plenty of evidence that this is a complicated issue. It’s not rocket science, it’s much more complicated because it’s living organisms.    
-Jeffrey Smith  https://www.responsibletechnology.org/was-covid-19-genetically-engineered/

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