Tuesday, March 28, 2023
Astaxanthin vs Spirulina for Eye Health
-Messenger from Himalayas by N. Roerich
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the zebrafish can repair and regenerate its heart, brain, retina, pancreas, spine, fins, and kidneys.
That’s good news for us, because not only do zebrafish and humans have the same major organs and tissues, we share more than 80% of the same genes associated with human disease. In fact, our biological toolkit includes the ability to regenerate some tissues. Humans regenerate skin every 27 days, bones when they’re broken, the liver when it’s injured, and red blood cells every four to eight weeks. Understanding the zebrafish’s remarkable capacity to regrow injured organs could one day allow humans to regenerate eyes, hearts, and spines.
…Mruk wants to know how zebrafish use electricity to tell cells when to increase inflammation, and when to resolve it. Too much inflammation leads to lasting damage. Using electrodes, she measures how electricity across the entire zebrafish spine changes after injury and uses three-dimensional imaging to see which cells are also changing in response to the electricity. “What does the fish do electrically that lets the spine recover?” she asks. “Can we apply that to humans?….
“You can blind or seriously damage a zebrafish, and they will regrow their eye in a matter of weeks,” says James Patton, a biologist at Vanderbilt University. The fish can do this because of those Müller glia cells in the retina. Behaving like stem cells, they can regrow the retina and replace all the damaged neurons. “The amazing thing is that humans have the same exact Müller glia cell,” says Patton. “But ours doesn’t respond to damage the same way.”
Understanding exactly how the fish Müller glia cells turns into a stem cell might help us trick our own Müller glia cells to do the same thing, perhaps with an injectable medication into the eye.
In related research, Patton and colleagues found that the Müller glia were stimulated to become like stem cells and proliferate when levels of the neurotransmitter gamma-aminobutyric acid (GABA) were reduced. The neurotransmitter GABA puts the breaks on cell signaling, and scientists now wonder if it also plays a role in regeneration. When GABA levels are high, the stem cells stay quiet, and if GABA levels fall, then the stem cells start to divide. Patton now plans to explore whether inhibiting GABA signaling might trigger regeneration in the retina of mice. Perhaps someday we will be able to do the same in humans who have injured retinas or are going blind. https://www.brainfacts.org/in-the-lab/animals-in-research/2020/researching-regeneration-through-the-zebrafish-100520
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Health ·Nov 07, 2022
Astaxanthin vs Spirulina for Eye Health
by Dr. Jewel Alfoure, ND
Eye health is a critical part of wellness, but it seems like common knowledge about nutrients that support eye health is limited. There are many different eye health supplements on the market, and it is therefore very difficult to decide which one is right for you. In this article we will compare astaxanthin and spirulina, two popular eye health supplements. We will look at the benefits of each nutrient and discuss how they might help improve eye health.

Astaxanthin is a powerful antioxidant that has been shown to provide a wide range of health benefits. It is most commonly found in fish, but it can also be derived from other sources such as algae and krill. It is this pigment that gives salmon its pink colour (1). As an antioxidant, astaxanthin helps to protect cells from damage caused by inflammation and free radicals. Additionally, it has been shown to support the immune system and promote healthy skin and eyesight. Astaxanthin is a potent nutrient that offers numerous health benefits. (2)
Astaxanthin clinical studies have shown this substance to have a variety of medicinal benefits. For example, it has been shown to improve heart health, cognitive function and joint pain. In addition clinical findings have demonstrated that astaxanthin can help to protect against certain types of unwanted growths (4). As a result, clinical trials are ongoing in order to determine the most effective ways to use this substance for the treatment of various medical conditions. However more research is needed in order to fully understand the potential of astaxanthin. (5)
Astaxanthin is a powerful antioxidant that can help to protect against Sun radiation damage (6). Studies have shown that astaxanthin can reduce UV-induced oxidative stress in the eye and skin. It has also been shown to increase the skin's resistance to sunburn. Studies have shown that astaxanthin is more effective than other common antioxidants such as Vitamin C and Vitamin E (7). In addition astaxanthin can help to protect the eyes from photo-oxidative damage. These effects make astaxanthin an important tool for protecting against the harmful effects of radiation from the sun. (8)

Occular health is the health of the eye. The Occular System includes the eyeball, muscles, eyelids, tear glands, optic nerve and other surrounding tissues. All these structures must work together properly to provide clear vision. The cornea and lens of the eye are instruments to focus the light on the retina, which converts the light into electrical signals that are sent to the brain via the optic nerve. (9)
The retina is a thin layer of tissue forming the back layer of the eye. That layer contains cells that are sensitive to light (photoreceptors).
Types of Phtoreceptors in the eye:
Rods allow us to see the big picture, they are responsible for vision in dim light (scotopic vision), Cones are responsible for fine details including colour vision (photopic vision). (9)
Recent studies have shown that astaxanthin may also be beneficial for eye health. One study found that astaxanthin was able to improve visual acuity and night vision in healthy adult subjects. Another study found that astaxanthin supplementation was able to significantly improve subjective symptoms of eye fatigue in office workers. (10)

How Does Astaxanthin Work?
In several tirals participants who took astaxanthinhad significant improvements in visual acuity and visual contrast sensitivity. The study also found that astaxanthin improved night vision, with participants reporting fewer halos and glares around lights. A number of studies hypothesize that astaxanthin likely works by protecting the eyes from oxidative stress, which can damage the retina and lead to vision problems. In addition, astaxanthin has been shown to promote the production of enzymes that protect the retina from light-induced damage. Thus, astaxanthin is usually included as an ingredient in many eye health support formulas. (2, 11)
Sources of Astaxanthin
Astaxanthin can be found in a variety of natural sources, including certain types of algae and seafood. It can also be produced by the process of chemical synthesis in a laboratory. Both natural and synthetic astaxanthin have been shown to provide health benefits, but there are some important differences between the two. For example, natural astaxanthin is generally more bioavailable than synthetic astaxanthin, meaning that it is better absorbed by the body. In addition natural astaxanthin is usually derived from the microalgae Haematococcus Pluvialis, which is a rich source of this antioxidant. Synthetic astaxanthin, on the other hand, is often produced from chemical precursors that may not be as beneficial to human health. Thus it is best to research the highest quality astaxanthin to ensure the safety and potency of consumed eye health formulas. (12)
It may also be important to ask about the stability of the astaxanthin in the formula, higher doses may be used to ensure the potency of dietary supplements as astaxanthin does have a rate of breakdown. Sitting on the shelf for a long time may reduce the maximum antioxidant capacity, reduce the anti-inflammatory protection it provides and reduce the potency of the dietary supplement. (13-14)
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Top 5 Other Health Benefits of Astaxanthin
1. Powerful Antioxidant: Astaxanthin is a powerful antioxidant that can help to protect the body against damage caused by free radicals. Free radicals are unstable molecules that can cause cell damage and lead to various diseases. Astaxanthin is thought to be one of the most powerful antioxidants, and it has been shown to be effective in reducing inflammation and protecting cells from damage. (15)
2. May Boost Brain Health: Astaxanthin has also been shown to boost brain activity and health. A study published in the journal Nutritional Neuroscience found that astaxanthin was able to improve memory performance and cognitive function in rats. The study’s authors suggest that astaxanthin may be beneficial for preventing age-related cognitive decline. (16)
3. May Improve Heart Health: Astaxanthin may also improve cardiovascular health. A study published in the journal of Plant Foods for Human Nutrition found that astaxanthin may reduce cholesterol levels and inflammation in humans. The study’s authors suggest that astaxanthin may be beneficial for improving human lipid profiles and reducing oxidative stress and thus, preventing heart disease. (17)
4. May Enhance Exercise Performance: Astaxanthin has also been shown to enhance exercise performance. A study published in the International Journal of Sports Medicine found that astaxanthin was able to improve endurance and reduce muscle soreness in cyclists. The study’s authors suggest that astaxanthin may be beneficial for athletes or anyone looking to improve their physical performance. (18)
5. May Protect Against UV Damage: Astaxanthin has also been shown to protect against UV damage. A study published in the Journal of Investigative Dermatology found that astaxanthin was able to protect human skin cells from damage caused by UV radiation. The study’s authors suggest that astaxanthin may be an effective sunscreen ingredient or supplement for people who are exposed to sunlight regularly. Other studies also find evidence that astaxanthin may improve skin elasticity and reduce the visible signs of ageing. (19)
What is Spirulina?
Spirulina is a blue-green algae that is rich in nutrients. It is often taken as a supplement for its many health benefits. Some of these benefits include improved eye health, better gut health, and support in immunity.
Spirulina is high in protein (including some essential amino acids), vitamins (including vitamin K), minerals, and antioxidants. It also has anti-inflammatory properties. Spirulina can help to boost the immune system, improve digestion, and reduce the risk of chronic diseases. Some research suggests that spirulina may also be effective in treating allergies, anemia, and fatigue. (20)
Preliminary studies suggest that spirulina may bind to heavy metals in the gut, preventing their absorption. It may also help to promote the excretion of these toxins. (21)
Clinical Trials Studying Spirulina
In a study done on rats, it was found that spirulina prevented retinal damage caused by diabetes. The rats were given spirulina for 12 weeks and researchers found that there was a significant decrease in markers of oxidative stress and inflammation in the rats’ eyes. (22)
In another study spirulina may improve symptoms of xerophthalmia (an eye condition caused by vitamin A deficiency). After 10 weeks, it was found that the children had increased levels of carotene in their blood. Carotene is converted into vitamin A in the body and is important for eye health. (21, 23)

Spirulina for Eye Health
Spirulina contains high levels of beta carotene; human consumption of beta carotene leads to its conversion into vitamin A without the risk of toxicity Vitamin A is important for eye health because it helps to prevent night blindness and dry eyes. It also has an overall positive effect on eye health as it helps to protect the surface of the eye from infection. (23, 24)
How Does Spirulina Work?
Spirulina works for eye health because it contains high levels of beta-carotene, which is converted into vitamin A in the body.
Zeaxanthin is a yellow pigment found in a variety of fruits and vegetables, as well as in the green microalgae spirulina. It is an important nutrient for human health and has been shown to play a role in protecting against age-related macular degeneration (25).
Zeaxanthin is thought to work by absorbing blue light, which can damage the retina, and by providing antioxidant protection against free radicals. The best food sources of zeaxanthin are dark leafy greens, such as spinach and kale, as well as orange vegetables like sweet potatoes and carrots. Spirulina is also a rich source of pigment and provides numerous other health benefits as well. Supplementation with zeaxanthin may be beneficial for people at risk for macular degeneration, and for those who do not consume enough fruits and vegetables (26).
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